JNTU
JNTU B.Pharmacy III PHARMACOGNOSY AND PHYTOCHEMISTRY-II Previous Question Paper (July/August - 2023 - R17)
Note: i) Question paper consists of Part A, Part B.
ii) Part A is compulsory, which carries 25 marks. In Part A, Answer all questions.
iii) In Part B, Answer any one question from each unit. Each question carries 10 marks and may have a, b as sub questions.
Part A
List out different secondary metabolites of pharmaceutical importance with example.
Answer
Secondary metabolites include: Alkaloids (e.g., Atropine), Glycosides (e.g., Digoxin), Terpenoids (e.g., Menthol), Phenolics (e.g., Tannins), and Flavonoids (e.g., Rutin).
Give the schematic representation of primary and secondary metabolites derived from carbon metabolism in plants.
Answer
Photosynthesis produces glucose, which enters primary metabolism (glycolysis, TCA cycle, pentose phosphate pathway) to form precursors like amino acids, acetyl-CoA, and mevalonic acid. These precursors then serve as the building blocks for secondary metabolic pathways, leading to the synthesis of alkaloids, terpenoids, and phenolics.
Mention the source, chemical composition and therapeutic uses of Mentha.
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Give the biological source and uses of opium.
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Write the source and chemical constituents of Bitter Almond.
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Explain modified Borntrager'test and Test for Abietic acid in colophony.
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Define glycoside. Give Chemical structure of any one glycoside.
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State the uses of Rutin and Citral.
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Give the botanical source and uses of Forskolin.
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Discuss the estimation of Caffeine.
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Part B
Explain in detail about the Acetate pathway.
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Write a note on competitive feeding and sequential analysis.
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How do you prepare radioactive isotopes? Explain.
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Discuss about precursor product sequence and Double and multiple labelling.
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Write chemical composition and uses of Liquorice.
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Discuss in detail about the biological source and therapeutic uses of Rauwolfia.
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Describe various general methods of extraction of Vinca alkaloids.
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Give a brief note on Lignans.
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Write the source, test for identification and uses of Asafoetida.
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Give a brief note on Gentian.
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Discuss the chemical constituents, identification tests and uses of Senna.
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Give the source, chemical constituents and identification tests of Myrrh.
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Describe the isolation and identification of Atropine.
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Give a brief note on Artemisin.
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Write various Identification tests and analytical procedures for Quinine and Podophyllotoxin.
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Give the industrial production and estimation of Digoxin.
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Explain the industrial production and estimation of Sennoside.
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Give a descriptive note on various modern methods of extraction. Add a note on its advantages.
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