JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Overview

I. Introduction to Equipment and Glassware

• 1. Determination of melting point/boiling point by Thiels method.
• 2. Determination of Mixed melting point for organic compounds.
• 3. Recrystallization (Purification including decolourization) of two organic compounds.
• 4. Purification and drying of organic solvents. II. Preparation of organic compounds (each involving a specific organic reaction covered in theory)
• 1. N-Acetylation : Preparation of Acetanilide from Aniline
• 2. O-Acetylation : Preparation of Aspirin from Salicylic acid
• 3. Nuclear Bromination : Preparation of p-Bromoacetanilide from Acetanilide
• 4. Hydrolysis : Preparation of p-Bromoaniline from p-Bromoacetanilide
• 5. Nuclear Nitration : Preparation of m-Dinitrobenzene from nitrobenzene
• 6. Oxidation : Preparation of Benzoic acid from Benzyl chloride
• 7. Esterification : Preparation of n-Butylacetate from n-Butylalcohol
• 8. Etherification : Preparation of -Naphthyl methyl ether from -Naphthol
• 9. -Halogenation : Preparation of Iodoform from Oxidation of Acetone
• 10. Extensive Nuclear : Preparation of Tribromophenol or Bromination Substitution Tribromoaniline from Phenol or Aniline III. Systematic qualitative Analysis (Identification) of Monofunctional Organic Compounds: Avoid water-soluble compounds, and compounds containing more than one functional group; at least six individual compounds to be analyzed.

References

• 1. Vogel’s Text Book of Practical Organic Chemistry, 5th Edition.
• 2. R. K. Bansal, Laboratory Manual of Organic Chemistry.
• 3. O. P. Agarwal Advanced Practical Organic Chemistry.
• 4. F. G. Mann and B.C. Saunders, Practical Organic Chemistry.
• 5. Organic Chemistry a lab manual, Cengage learning India Pvt. Ltd. By Pavia
• 6. Advanced Practical Organic Chemistry, Vishoi-Vikas Publications.