JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objectives

Helps the students in getting exposed to method s of extraction

Course Outcome

Helps the students to understand the organization and research of natural

products in herbal drugs industries.

UNIT - I

Herbal Extracts: types of Extraction methods such as Maceration, Percolation, Super critical fluid extraction and Ultra – Sonic extraction Equipment for preparing herbal extracts: Process and equipments-Name of the equipment and its uses with merits and demerits in each of the following unit operations in the extraction process.

• 1. Size reduction 4.Evaporation/Distillation
• 2. Extraction 5.Solvent recovery
• 3. Filtration 6. Drying of extracts

UNIT - II

Excipients: Definition ,classification of natural Excipients: Source, chemical ,nature, description parameters pharmaceutical uses and storage condition of following natural excipients, binding agents, disintegrating agents, diluents, emulsifying agent: Acacia, Tragacanth, Alginates, CMC, Gelatine, Pectin, Lactose, Starches, Talc, Ointment bases, suppository bases and Hardening agents: Bees wax, Cocoa butter, Lanolin, Hard Paraffin.

UNIT - III

Manufacturing: Methods of Preparation and Evaluation of Herbal Tablets, Capsules, Semisolid dosage forms and liquids- study of any tree formulations under each category with respect to their formulas and claims for various herbs used in them.

UNIT - IV

Herbal drug Standardization:

• a) Definition and Need for the study of standardization. General flow of activities in standardization.
• b) WHO guidelines on standardization Parameters: Botanical, Physic Chemical, Pharmacological, Toxicological standardization.

UNIT - V

• a) Name of the different companies’ manufacturing different herbal extracts, standardized extracts with concentration of marker compounds, active principles and claims regarding their uses.
• b) Herbal drug regulatory Affairs:Introduction, objectives of Herbal Drug Regulation, Current Status of Herbal Drug Regulatory Affairs.

TEXT BOOKS:

• 1. Textbook of Pharmacognosy by G.E.Trease, W.C.Evans,ELBS
• 2. Textbook of HPTLC by P.D. Seth.
• 3. Herbal Perfumes and cosmetics by Panda REFRENCES:
• 1. Pharmacognosy by V.E Tyler, LR Brandy and JE Robbers (KM Varghese & co., Mumbai)
• 2. Indian Pharmacopoeia