JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objectives

This subject will provide an opportunity for the student to learn about the drug

with regard to classification, pharmacodynamic and pharmacokinetic aspects, adverse effects, uses, dose, and route of administration, precautions, contraindications and interaction with other drugs.

Course Outcome

Understand the pharmacological aspects of drugs, importance of pharmacology

subject as a basis of therapeutics and correlate the knowledge therapeutically.

UNIT - I

General Pharmacology: Introduction to pharmacology, sources of drugs, dosage forms and routes of administration, Absorption, distribution, Metabolism and excretion of drugs, mechanism of action, combined effect of drugs, factors modifying drug action, Adverse drug reactions, tolerance and dependence, pharmacogenetics., principles of drug discovery and phases of drug development.

UNIT - II

Pharmacology of Peripheral Nervous System:

• a. Neurohumoral transmission (autonomic and Somatic)
• b. Parasympathomimetics, parasympatholytics, sympathomimetics & sympatholytics
• c. Skeleton muscle relaxants

UNIT - III

Pharmacology of Central Nervous System:

• a. Neurohumoral transmission in the C.N.S.
• b. General anesthetics.
• c. Alcohols and disulfiram.
• d. Pharmacology of Sedatives, hypnotics, anti-anxiety agents .

UNIT - IV

• a. Analgesics, Antipyretics, Anti-inflammatory and Anti-gout drugs.
• b. Narcotic analgesics and antagonists.
• c. C.N.S. stimulants
• d. Drug Addiction and Drug Abuse.
• e. Local anesthetic agents

UNIT - V

• a. Psychopharmacological agents (antipsychotics) Antidepressants, anti- maniacs and hallucinogens.
• b. Pharmacology of Anti-epileptic drugs
• c. Anti-Parkinsonian Drugs

TEXT BOOKS

• 1. Tripathi, Textbook of Pharmacology, JAYPEE
• 2. F.S.K Barar, Essentials of Pharamcotheraptics.
• 3. H.P Rang, M. M. dale & J.M. Ritter, Pharmacology,: Churchill Living stone, 4th Ed.

REFERENCES

• 1. Sathoskar, Pharmacology and pharmaco therapeutics Vol. 1 & 2, Publ by Popular Prakashan, Mumbai.
• 2. Pharmacology, An illustrated review by Mark A Simmons