JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
PS707: BIOPHARMACEUTICS AND PHARMACOKINETICS LAB
B.Pharmacy IV Year I Semester (R16)
List of Experiments
1. Estimation of various Pharmacokinetic parameters from the given data
2. Influence of dosage form on dissolution behaviour of same API
3. Influence of Physico-chemical properties (Particle size, salt form, crystalline form) on dissolution rate of drug substances.
4. Approaches to enhance the dissolution rate of drugs i.e.,i) Cyclodextrin complexation
ii) Inclusion of Hydrophilic polymers such as PVP, PEG.
iii) Co-solvency
5. Absorption studies – invitro and invivo
6. Determination of rate of clearance
7. Statistical treatment of Pharmaceutical data Ie.,
i) test ii) Chi-square test iii) ANOVA
Reference book
1. Dr. D. Dhachinamoorthi- Biopharmaceutical and Pharmacokinetic- A Practical Manual R16 B.PHARMACY IV YEAR
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