JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

PC406: MEDICINAL CHEMISTRY – I LAB

B.Pharmacy II Year II Semester (R17)

List of Experiments:

I Preparation of drugs/ intermediates 1 1,3-pyrazole 2 1,3-oxazole 3 Benzimidazole 4 Benztriazole 5 2,3- diphenyl quinoxaline 6 Benzocaine 7 Phenytoin 8 Phenothiazine 9 Barbiturate

II Assay of drugs 1 Chlorpromazine 2 Phenobarbitone 3 Atropine 4 Ibuprofen 5 Aspirin 6 Furosemide

III Determination of Partition coefficient for any two drugs

Recommended Books (Latest Editions)

  • 1. Wilson and Giswold’s Organic medicinal and Pharmaceutical Chemistry.
  • 2. Foye’s Principles of Medicinal Chemistry.
  • 3. Burger’s Medicinal Chemistry, Vol I to IV.
  • 4. Introduction to principles of drug design- Smith and Williams.
  • 5. Remington’s Pharmaceutical Sciences.
  • 6. Martindale’s extra pharmacopoeia.
  • 7. rganic Chemistry by I.L. Finar, Vol. II.
  • 8. The Organic Chemistry of Drug Synthesis by Lednicer, Vol. 1-5.
  • 9. Indian Pharmacopoeia.
  • 10. Text book of practical organic chemistry- A.I. Vogel

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