JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Overview

Scope: This subject deals with classification and nomenclature of simple organic compounds, structural isomerism, intermediates forming in reactions, important physical properties, reactions and methods of preparation of these compounds. The syllabus also emphasizes on mechanisms and orientation of reactions.

Course Objectives

Upon completion of the course the student shall be able to

• write the structure, name and the type of isomerism of the organic compound
• write the reaction, name the reaction and orientation of reactions
• account for reactivity/stability of compounds,
• identify/confirm the identification of organic compound General methods of preparation and reactions of compounds superscripted with asterisk (*) to be explained To emphasize on definition, types, classification, principles/mechanisms, applications, examples and differences

UNIT - I

Classification, nomenclature, and isomerism Classification of Organic Compounds, Common and IUPAC systems of nomenclature of organic compounds, (up to 10 Carbons open chain and carbocyclic compounds), Structural isomerisms in organic compounds

UNIT - II

Alkanes*, Alkenes* and Conjugated dienes* SP3 hybridization in alkanes, Halogenation of alkanes, uses of paraffins. Stabilities of alkenes, SP2 hybridization in alkenes E1 and E2 reactions – kinetics, order of reactivity of alkyl halides, rearrangement of carbocations, Saytzeffs orientation and evidences. E1 verses E2 reactions, Factors affecting E1 and E2 reactions. Ozonolysis, electrophilic addition reactions of alkenes, Markownikoff’s orientation, free radical addition reactions of alkenes, Anti Markownikoff’s orientation. Stability of conjugated dienes, Diel-Alder, electrophilic addition, free radical addition reactions of conjugated dienes, allylic rearrangement

UNIT - III

Alkyl halides* SN1 and SN2 reactions - kinetics, order of reactivity of alkyl halides, stereochemistry and rearrangement of carbocations. SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions Structure and uses of ethylchloride, Chloroform, trichloroethylene, tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform. Alcohols*- Qualitative tests, Structure and uses of Ethyl alcohol, chlorobutanol, Cetosterylalcohol, Benzyl alcohol, Glycerol, Propylene glycol

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UNIT - IV

Carbonyl compounds* (Aldehydes and ketones) Nucleophilic addition, Electromeric effect, aldol condensation, Crossed Aldol condensation, Cannizzaro reaction, Crossed Cannizzaro reaction, Benzoin condensation, Perkin condensation, qualitative tests, Structure and uses of Formaldehyde, Paraldehyde, Acetone, Chloral hydrate, Hexamine, Benzaldehyde, Vanilin, Cinnamaldehyde.

UNIT - V

Carboxylic acids* Acidity of carboxylic acids, effect of substituents on acidity, inductive effect and qualitative tests for carboxylic acids, amide and ester Structure and Uses of Acetic acid, Lactic acid, Tartaric acid, Citric acid, Succinic acid. Oxalic acid, Salicylic acid, Benzoic acid, Benzyl benzoate, Dimethyl phthalate, Methyl salicylate and Acetyl salicylic acid Aliphatic amines* - Basicity, effect of substituent on Basicity. Qualitative test, Structure and uses of Ethanolamine, Ethylenediamine, Amphetamine

TEXTBOOKS

(Latest Editions)

• 1. Organic Chemistry by Morrison and Boyd
• 2. Organic Chemistry by I. L. Finar , Volume-I
• 3. Textbook of Organic Chemistry by B.S. Bahl & Arun Bahl.
• 4. Organic Chemistry by P. L. Soni
• 5. Practical Organic Chemistry by Mann and Saunders.
• 6. Vogel’s text book of Practical Organic Chemistry
• 7. Advanced Practical organic chemistry by N.K. Vishnoi.
• 8. Introduction to Organic Laboratory techniques by Pavia, Lampman and Kriz.
• 9. Reaction and reaction mechanism by Ahluwaliah / Chatwal. [Type text] [Type text]