JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objectives

Cell biology is a branch of biology that studies cells – their physiological

properties, their structure, the organelles they contain, interactions with their environment, their life cycle, division, death and cell function. This is done both on a microscopic and molecular level. Cell biology research encompasses both the great diversity of single-celled organisms like bacteria and protozoa, as well as the many specialized cells in multi-cellular organisms such as humans, plants, and sponges.

Course Outcomes

Upon completion of the subject student shall be able to:

• Summarize cell and molecular biology history.
• Summarize cellular functioning and composition.
• Describe the chemical foundations of cell biology.
• Summarize the DNA properties of cell biology.
• Describe protein structure and function.
• Describe cellular membrane structure and function.
• Describe basic molecular genetic mechanisms.
• Summarize the Cell Cycle

UNIT - I

• a. Cell and Molecular Biology: Definitions theory and basics and Applications.
• b. Cell and Molecular Biology: History and Summation.
• c. Theory of the Cell? Properties of cells and cell membrane.
• d. Prokaryotic versus Eukaryotic
• e. Cellular Reproduction
• f. Chemical Foundations – an Introduction and Reactions (Types)

UNIT - II

• a. DNA and the Flow of Molecular Structure
• b. DNA Functioning
• c. DNA and RNA
• d. Types of RNA
• e. Transcription and Translation

UNIT - III

• a. Proteins: Defined and Amino Acids
• b. Protein Structure
• c. Regularities in Protein Pathways
• d. Cellular Processes
• e. Positive Control and significance of Protein Synthesis

UNIT - IV

• a. Science of Genetics
• b. Transgenics and Genomic Analysis
• c. Cell Cycle analysis
• d. Mitosis and Meiosis
• e. Cellular Activities and Checkpoints R17 B. PHARMACY III YEAR

UNIT - V

• a. Cell Signals: Introduction
• b. Receptors for Cell Signals
• c. Signaling Pathways: Overview
• d. Misregulation of Signaling Pathways
• e. Protein-Kinases: Functioning Recommended Books (latest edition):
• 1. Ananthanarayana and Panikers, Text book of microbiology, 10th edition by universities press.
• 2. W.B. Hugo and A.D. Russel: Pharmaceutical Microbiology, Blackwell Scientific publications, Oxford London.
• 3. Prescott and Dunn., Industrial Microbiology, 4th edition, CBS Publishers & Distributors, Delhi.
• 4. Pelczar, Chan Kreig, Microbiology, Tata McGraw Hill edn.
• 5. Malcolm Harris, Balliere Tindall and Cox: Pharmaceutical Microbiology.
• 6. Rose: Industrial Microbiology.
• 7. Probisher, Hinsdill et al: Fundamentals of Microbiology, 9th ed. Japan
• 8. Cooper and Gunn’s: Tutorial Pharmacy, CBS Publisher and Distribution.
• 9. Peppler: Microbial Technology.
• 10. Edward: Fundamentals of Microbiology.
• 11. N.K.Jain: Pharmaceutical Microbiology, Vallabh Prakashan, Delhi
• 12. Bergeys manual of systematic bacteriology, Williams and Wilkins- A Waverly company
• 13. B.R. Glick and J.J. Pasternak: Molecular Biotechnology: Principles and Applications of Recombinant DNA: ASM Press Washington D.C.
• 14. RA Goldshy et. al., Kuby Immunology. R17 B. PHARMACY III YEAR