JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objectives

This subject deals with general methods of preparation and reactions of someorganic

compounds. Reactivity of organic compounds are also studied here. The syllabus emphasizes on mechanisms and orientation of reactions. Chemistry of fats and oils are also included in the syllabus.

Course Outcomes

Upon completion of the course the student shall be able to

• write the structure, name and the type of isomerism of the organic compound
• write the reaction, name the reaction and orientation of reactions
• account for reactivity/stability of compounds,
• prepare organic compounds

UNIT - I

Benzene and its derivatives A. Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture, resonance in benzene, aromaticcharacters, Huckel’s rule B. Preparations of benzene, Reactions of benzene - nitration, sulphonation, halogenation reactivity, Friedelcrafts alkylation- reactivity, limitations, Friedelcrafts acylation. C. Substituents, effect of substituents on reactivity and orientation ofmono substituted benzene compounds towards electrophilicsubstitution reaction

UNIT - II

Phenols* - preparation and reactions, Acidity of phenols, effect of substituents on acidity, qualitativetests. Aromatic Amines* - Basicity of amines, effect of substituents on basicity, and synthetic uses of aryl diazonium salts Aromatic Acids* –Acidity, effect of substituents on acidity and important reactions of benzoic acid.

UNIT - III

Nitro Compounds: Preparations and reactions, Classification, Reactivity: Halogenation using nitrous acid, Nef reaction, Michael Addition, Henry Reaction, Aromatic Nitro hydrocarbons, Preparation of Nitrobenzene from diazonium salt and direct nitration, Reactivity and reduction of nitrobenzene in different media. Ethers (aliphatic and aromatic): Introduction, synthesis and reactions of ethers

UNIT - IV

Polynuclear hydrocarbons:

• a) Synthesis, reactions
• b) Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane, Triphenylmethane and their derivatives

UNIT - V

Cyclo alkanes: Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and cyclobutane

RECOMMENDED BOOKS (Latest Editions)

• 1. Organic Chemistry by Morrison and Boyd
• 2. Organic Chemistry by I.L. Finar, Volume-I
• 3. Textbook of Organic Chemistry by B.S. Bahl & Arun Bahl.
• 4. Pharmaceutical organic Chemistry by V Algarsamy, Pharmamed Press
• 5. Organic Chemistry by P.L. Soni
• 6. Practical Organic Chemistry by Mann and Saunders.
• 7. Vogel’s text book of Practical Organic Chemistry
• 8. Advanced Practical organic chemistry by N.K. Vishnoi.
• 1. Introduction to Organic Laboratory techniques by Pavia, Lampman and Kriz.