JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

PS407: PHARMACOLOGY – I LAB

B.Pharmacy II Year II Semester (R22)

List of Experiments:

  • 1. Introduction to experimental pharmacology.
  • 2. Commonly used instruments in experimental pharmacology.
  • 3. Study of common laboratory animals.
  • 4. Maintenance of laboratory animals as per CPCSEA guidelines.
  • 5. Common laboratory techniques. Blood withdrawal, serum and plasma separation, anesthetics and euthanasia used for animal studies.
  • 6. Study of different routes of drugs administration in mice/rats.
  • 7. Study of effect of hepatic microsomal enzyme inducers on the phenobarbitone sleeping time in mice.
  • 8. Effect of drugs on ciliary motility of frog oesophagus
  • 9. Effect of drugs on rabbit eye.
  • 10. Effects of skeletal muscle relaxants using rota-rod apparatus.
  • 11. Effect of drugs on locomotor activity using actophotometer.
  • 12. Anticonvulsant effect of drugs by MES and PTZ method.
  • 13. Study of stereotype and anti-catatonic activity of drugs on rats/mice.
  • 14. Study of anxiolytic activity of drugs using rats/mice.
  • 15. Study of local anesthetics by different methods

Note

All laboratory techniques and animal experiments are demonstrated by simulated experiments by

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RECOMMENDED BOOKS (Latest Editions)

  • 1) Essentials of Experimental Pharmacology, General Concepts by Bothra Sunil

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