JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Pre-requisites

Nil

UNIT - I: Classification of materials used in medicine, Properties of Materials

UNIT - II

Host reactions to: Inflammation, Wound healing and the Foreign body response. Systemic toxicity and Hypersensitivity. Blood coagulation and Blood-materials Interactions. Tumorigenesis. Testing biomaterials: In Vitro assessment of tissue compatibility In vivo assessment of tissue compatibility. Testing of blood-materials interactions. Degradation of materials in the biological environment: Effects of the Biological environment on metals, polymers, and ceramics.

UNIT - III

Applications of materials in medicine, Dentistry and Biology: Cardiovascular medical devices. Nonthrombogenic treatments and Strategies. Dental implantation adhesive and Sealants. Ophthalmologic applications-intraocular lens implants.

UNIT - IV

Orthopedic biomaterials, Materials for fixation screws, plates, intramedullar nails. Sutures. Burn dressings and Skin substitutes. Artificial organs and tissues: Implantable cardiac assist devices. Materials for extracorporeal devices. Cochlear implants. Artificial red blood cell substitutes.

UNIT - V

Sterilization of implants and Devices implants and Device failure. Implant retrieval and Evaluation. Standards development and regulation of medical products using biomaterials. Nano bio materials.

TEXT BOOKS:

• 1. Biomaterials Science: An Introduction to Materials in Medicine Buddy D. Ratner, Frederick J. Schoen, Allan S. Hoffman, Jack E. Lemons
• 2. Hench L L Ethridg E.C. Biomaterials, an interfacial approach, Academic press 1982

REFERENCE BOOKS:

• 1. Bronzino J D, The Handbook Biomedical Engineering, CRC Press. R16 B.TECH BIOMEDICAL ENGG.