JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objective

The subject imparts basic knowledge of toxicology. This information will make

the student Competent in various toxicologies of liver, neuro, kidney etc

Course Outcome

Upon completion of the course, the student shall be able to,

• Explain the various toxicologies
• Explain various toxicologies of lungs, liver, gentic etc
• Appreciate the importance and mechanism of skin and reproductive toxicology
• Explain various mechanisms and affects of pesticides

UNIT - I: Introduction to General Toxicology

History of toxicology, classification of toxicology, toxicants exposure, routes exposure and exposure characterization. animal and plant toxins, mechanisms of toxicity, toxicokinetics, biotransformation of xenobiotics.

UNIT - II

Toxicology of the liver, Toxicology of the Lung, Chemical Carcinogenesis & Genetic Toxicology

UNIT - III

Neurotoxicology, Cardiovascular Toxicology, Molecular Toxicology & Toxicogenomics, Immuno- toxicology, Toxicology of the Kidney

UNIT - IV

Toxicology of the Intestine, Toxicology of the Skin, Reproductive Toxicology & Teratology, Risk Assessment

UNIT - V

Nanotoxicology, Ecotoxicology, Toxicology of Metals, Analytical/Forensic Toxicology, Toxic Effects of Pesticides, Pesticide Regulation at EPA

REFERENCE BOOKS:

• 1. Casarett & Doull's Essentials of Toxicology by Curtis D. Klaassen, John B. Watkins
• 2. Principles of Toxicology by Karen Stine, Thomas M. Brown
• 3. Text Book of Pathology by Harsh Mohan R19 M.PHARM PHARMACOLOGY M.Pharm I Year I Sem (Pharmacology)