JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

ADVANCED MEDICINAL CHEMISTRY – II LAB

M.Pharmacy I Year II Semester (R22)

List of Experiments: (Minimum of 10 experiments shall be conducted)

  • 1. Synthesis and characterization of the following drugs:
  • a. Phenacetin
  • b. Antipyrin
  • c. Benzocaine
  • d. Uramil
  • e. Tolbutamide
  • f. Phenothiazine
  • g. Isoniazid
  • h. Sulphasalazine
  • i. aspirin from salicylic acid
  • j. paracetamol from p-aminophenol
  • 2. Determination of partition coefficient of any medicinal compound by shake flask method.
  • 3. Any other relevant experiments based on theory.

REFERENCES:

  • 1. Lednicer D, Mitscher LA, The organic chemistry of drug synthesis, Volume-1-6. New York: A wiley-interscience publication; 2005.
  • 2. Mann FG, Saunders BC. Practical organic chemistry. 4th ed. New Delhi: Orient Longman; 2005.
  • 3. Furniss BS, Hanaford AJ, Smith PWG, Tatchell AR. Vogel’s textbook of practical organic chemistry. 5th ed. Singapore: Longman Singapore Publishers P Ltd; 1989.
  • 4. Vogel A. Elementary practical organic chemistry. Part 1: Small scale preparations. 2nd ed. New Delhi: CBS publishers and distributors; 2004. th
  • 5. Bansal RK. Laboratory manual of organic chemistry. 4 ed. New Delhi: New Age International (P) limited; 2005.
  • 6. Kar A. Advanced Practical Medicinal Chemistry. New Delhi: New Age International (P) limited; 2006.
  • 7. Indian Pharmacopoeia. Controller of Publication. Delhi, 1996.
  • 8. British Pharmacopoeia. British Pharmacopoeia Commission Office, London, 2008.
  • 9. United States Pharmacopoeia. United States Pharmacoepial Convention, Inc, USA, 2003. M.Pharm II Year I Sem (Pharmaceutical Chemistry)

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