JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objective

Helps the students to know about herbal remedies, common bitters, laxatives and

the analytical profiles of some herbal drugs used in everyday life.

Course Outcome

Upon completion of the course, the student shall be able to know the,

standardization and evaluation techniques, ethnobotany concepts, biological screening for the herbal drugs.

UNIT - I

Adulteration and Deterioration: Introduction, Types of Adulteration/ Substitution of Herbal drugs, Causes and Measures of Adulteration, Sampling Procedures, Determination of Foreign Matter, DNA Finger printing techniques in identification of drugs of natural origin, detection of heavy metals, pesticide residues, microbial contamination in herbs and their formulations.

UNIT - II

• a) A brief account on standardization parameters of herbal drugs.
• b) Analytical Profiles of herbal drugs: Andrographis paniculata, Boswellia serata, Coleus forskholii, Psoralea corylifolia.

UNIT - III

• a) Herbal remedies - Toxicity and Regulations: Herbals vs Conventional drugs, Efficacy of herbal medicine products, Validation of herbal therapies, Pharmacodynamic and Pharmacokinetic issues.
• b) Vegetable bitters: Biological source, Chemical Nature and description of bitter principles, and of the following – Chirata, Calumba, Cusparia, Serpentaria
• c) Vegetable Laxatives: Biological source, Chemical Nature and description of purgation actions and therapeutics of the following: Senna, Isapgul, agar, castor oil

UNIT - IV

Ethnobotany and Ethnopharmacology: Ethnobotany in herbal drug evaluation, Impact of Ethnobotany in traditional medicine, New development in herbals, Bio-prospecting tools for drug discovery, Role of Ethnopharmacology in drug evaluation, Reverse Pharmacology.

UNIT - V

Biological screening of herbal drugs: Introduction and need for Phyto Pharmacological screening, new strategies for evaluating Natural products, invitro evaluation techniques for antioxidants, antimicrobial. invivo evaluation of antiulcer, anticancer, wound healing, Hepatoprotectives

TEXT BOOKS:

• 1. Quality control of herbal drugs by P.K. Mukherjee
• 2. Standardization of botanicals by V. Rajpal, Vol I &II
• 3. Herbal Drug industry by Paridhavi
• 4. Pharmacognosy and Phytochemistry, A Comprehensive Approach 2nd Edition by S.L. Doore, S.S Khadabadi and B.A. Baviskar
• 5. A Text Book of Pharmacognosy by NPS Senegar, Ritesh Agarwal and Ashwini Singh

REFERENCE BOOKS:

• 1. Phytochemical methods of chemical analysis by Harbone
• 2. Indian herbal Pharmacopoeia
• 3. Dietetics by Sri Lakshmi
• 4. Herbal Drug industry by Chowdary M.Pharm I Year II Sem (PHARMACOGNOSY)