JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objectives

This course is designed to convey the knowledge necessary to understand

issues related to different kinds of hazard and their management. Basic theoretical and practical discussions integrate the proficiency to handle the emergency situation in the pharmaceutical product development process and provides the principle-based approach to solve the complex tribulations.

Course Outcome

At completion of this course it is expected that students will be able to;

• Understand about environmental problems among learners.
• Impart basic knowledge about the environment and its allied problems.
• Develop an attitude of concern for the industry environment.
• Ensure safety standards in pharmaceutical industry
• Provide comprehensive knowledge on the safety management
• Empower an ideas to clear mechanism and management in different kinds of hazard management system
• Teach the method of Hazard assessment, procedure, methodology for provide safe industrial atmosphere.

UNIT - I

Multidisciplinary nature of environmental studies: Natural Resources, Renewable and non-renewable resources, Natural resources and associated problems, a) Forest resources; b) Water resources; c) Mineral resources; d) Energy resources; e) Land resources Ecosystems: Concept of an ecosystem and Structure and function of an ecosystem. Environmental hazards: Hazards based on Air, Water, Soil and Radioisotopes.

UNIT - II

Air based hazards: Sources, Types of Hazards, Air circulation maintenance industry for sterile area and non-sterile area, Preliminary Hazard Analysis (PHA) Fire protection system: Fire prevention, types of fire extinguishers and critical Hazard management system.

UNIT - III

Chemical based hazards: Sources of chemical hazards, Hazards of Organic synthesis, sulphonating hazard, Organic solvent hazard, Control measures for chemical hazards, Management of combustible gases, Toxic gases and Oxygen displacing gases management, Regulations for chemical hazard, Management of over-Exposure to chemicals and TLV concept.

UNIT - IV

Fire and Explosion: Introduction, Industrial processes and hazards potential, mechanical electrical, thermal and process hazards. Safety and hazards regulations, Fire protection system: Fire prevention, types of fire extinguishers and critical Hazard management system mechanical and chemical explosion, multiphase reactions, transport effects and global rates. Preventive and protective management from fires and explosion electricity passivation, ventilation, and sprinkling, proofing, relief systems -relief valves, flares, scrubbers.

UNIT - V

Hazard and risk management: Self-protective measures against workplace hazards. Critical training for risk management, Process of hazard management, ICH guidelines on risk assessment and Risk management methods and Tools Factory act and rules, fundamentals of accident prevention, elements of safety Program and safety management, Physicochemical measurements of effluents,

BOD, COD, Determination of some contaminants, Effluent treatment procedure, Role of emergency services.

REFERENCE BOOKS:

• 1. Y.K. Sing, Environmental Science, New Age International Pvt, Publishers, Bangalore
• 2. “Quantitative Risk Assessment in Chemical Process Industries” American Institute of Chemical Industries, Centre for Chemical Process safety.
• 3. Bharucha Erach, The Biodiversity of India, Mapin Publishing Pvt. Ltd., Ahmedabad – 380 013, India,
• 4. Hazardous Chemicals: Safety Management and Global Regulations, T. S. S. Dikshith, CRC press
• 5. Safety and Health in Industry: A Handbook by AM Sarma, BS Publications M. Pharm I Year II Sem (Pharmaceutical Quality Assurance)