JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objectives

Helps the students in getting exposed to methods of extraction, preparation and

purification of herbal extracts. To acquire knowledge on the preparation and standardization of herbal preparation. They will expose to various research institutions of natural products.

Course Out comes: Helps the students to understand the organization and research of natural products in herbal drugs industries

UNIT - I

Equipment for preparing herbal extracts: Process and equipments- Name of the equipment and its uses with merits and demerits in each of the following unit operations in the extraction process.

• 1. Size reduction
• 2. Filtration
• 3. Evaporation/Distillation
• 4. Drying of extracts
• 5. Solvent recovery

UNIT - II

Definition, classification of natural excipients: Sources, Chemical nature, Description parameters Pharmaceutical uses and storage conditions of following Natural excipients Binding agents, disintegrating agents, diluents, emulsifying agents: Acacia, Tragacanth, Alginates, CMC, Gelatin, Pectin, Lactose, Starches, Talc, Ointment bases, suppository bases and Hardening agents: Beeswax, Cocoa butter, Lanolin, Hard paraffin

UNIT - III

Methods of preparation and Evaluation of Herbal Tablets, Capsules, Ointments and other dosage forms. Study of any three formulations under each category with respect to their formulas and claims for various herbs used in them

UNIT - IV

• a. Regulations and Claims – Current Products: Label Claims, Nutrient Content Claims, health claims, Dietary Supplements Claims.
• b. Food Laws and Regulations, FDA, FPO, MPO, BIS, AGMARK.

UNIT - V

• a) Natural colorants: Biological Source, coloring principles, chemical nature and usage of the following Annatto, Cochineal, Caramel, Henna, Indigo, Madder, Saffron, Turmeric
• b) Natural sweeteners:
• 1) Definition of nutritive and non-nutritive sweeteners, qualities of an ideal sweetener and sweetness potency.
• 2) Biological source, chemical nature, extraction details and usage of the following: Steviosides, Glycyrrhizin, Rebaudoside

REFERENCE BOOKS:

• 1. Textbook of Pharmacognosy by G. E. Trease, W. C. Evans, ELBS
• 2. Textbook of HPTLC by P.D. Seth.
• 3. Herbal Perfumes and cosmetics by Panda
• 4. Pharmacognosy by V.E Tyler, LR Brandy and JE Robbers (KM Varghese & co., Mumbai)
• 5. Natural Excipients by R. S Gaud, Surana.
• 6. Herbal Drug Technology By SL Deore
• 7. Herbal Drug industry by RD Chowdary
• 8. Herbal Drug Technology by SS Agarwal
• 9. Pharmacognosy and Phytochemistry by VD Rangari.
• 10. Indian Pharmacopoeia
• 11. Dietetics by Sri Lakshmi
• 12. Pharmaceutical Dosage forms - Tablets (Vol I, II and III) by Lieberman, Lachman and Schwartz.
• 13. Pharmaceutical Dosage forms - Capsules (Vol I, II and III) by Avis, Lieberman and Lachman. M.Pharm I Year II Sem (Pharmaceutical Chemistry)