JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objectives - To develop expertise regarding suitability and evaluation of nanomaterials, able

to apply the properties to the fabrication of nanopharmaceutical, evaluate the intensity of dosage forms and availability for targeting and controlled delivery.

Course Outcomes – The students should be able to select the right kind of materials, able to develop

nano formulations with appropriate technologies, evaluate the product related test and for identified diseases

UNIT - I: Introduction to Nanotechnology

• a) Definition of nanotechnology
• b) History of nanotechnology
• c) Unique properties and classification of nanomaterials
• d) Role of size and size distribution of nanoparticles properties.
• e) Marketed formulations based on nanotechnology and science behind them

UNIT - II: Synthesis of Nanomaterials

Physical, chemical and biological Methods

• a) Methods for synthesis of
• Gold nanoparticles
• Magnetic nanoparticles
• Polymeric nanoparticles
• Self – assembly structures such as liposomes, Niosomes, transferasomes, micelles, aquasomes and nanoemulsions

UNIT - III: Biomedical applications of Nanotechnology

• a) Nanotechnology products used for in vitro diagnostics
• b) Improvements to medical or molecular imaging using nanotechnology
• c) Targeted nanomaterials for diagnostic and therapeutic purpose

UNIT - IV

Design of nanomaterials for drug delivery, pulmonary and nasal drug delivery, nanomaterials for cancer therapy and cardiovascular diseases. Localized drug delivery systems.

UNIT - V

Characterization including the principles, size reduction, analysis of nanoparticles, size, PDI, size separation, stability, methods of analysis regarding integrity and release of drugs

RECOMMENDED BOOKS:

• 1. Nanomedicine and Nanoproducts: Applications, Disposition and Toxicology in the Human body, Eiki Igarashi, CRC press. 2015
• 2. Nanotechnology and Drug Delivery Volume one and two: Nanoplatforms in Drug Delivery, Jose L. Arias, CRC press
• 3. Nano: The Essentials: Understanding Nanosicence and Nanotechnology, T.Pradeep, Tata McGraw-Hill Publishing Company Limited, New Delhi, 2008.
• 4. Nanocrystals: Synthesis, Properties and Applications, C.N.R. Rao, P.J.Thomas and G.U. Kulkarni, Springer(2007)
• 5. Nanostructures and Nanomaterials: Synthesis, Properties and Application, Guozhong Gao, Imperial College Press (2004)
• 6. Nano chemistry:A Classical Approach to Nanomaterials – Royal Society for Chemistry, Cambridge, UK (2005)
• 7. Nanocomposite science and technology, pulickel M.Ajayan, Linda S. Schadler, paul V. Braun, Wiley-VCH Verlag, Weiheim (2003)
• 8. Nanoscale materials in chemistry, Edited by Kenneth J.Klabunde, John Wiley & Sons,2009
• 9. Nanoparticles as Drug carriers, Vladimir P Torchiling, Imperial College Press, USA, 2006
• 10. Introduction to Nano Science and Technologies, Ankaneyulu Yerramilli, BS Publications. 2016 M.Pharm I Year II Sem (Industrial Pharmacy)