JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objective

This course aims to enable the students to understand the different treatment

approaches in managing various disease conditions. Also, it imparts knowledge and skills in optimizing drug therapy of a patient by individualizing the treatment plan through evidence-based medicines.

Course Outcome

Upon completion of this course it is expected that students shall be able to:

• Describe and explain the rationale for drug therapy
• Summarize the therapeutic approach for management of various disease conditions including reference to the latest available evidence
• Discuss the clinical controversies in drug therapy and evidence-based medicine
• Prepare individualized therapeutic plans based on diagnosis
• Identify the patient specific parameters relevant in initiating drug therapy, and monitoring therapy (including alternatives, time- course of clinical and laboratory indices of therapeutic response and adverse effect/s). Etiopathogenesis and pharmacotherapy of diseases associated with following systems

UNIT - I

Cardiovascular System: Hypertension, Congestive cardiac failure, Acute coronary syndrome, Arrhythmias, Hyperlipidemias. Hematological diseases: Anemia, Deep vein thrombosis, Drug induced hematological disorders

UNIT - II

Respiratory System: Asthma, Chronic obstructive airways disease, Drug induced pulmonary diseases Endocrine system: Diabetes, Thyroid diseases

UNIT - III

Gastrointestinal System: Peptic ulcer diseases, Reflux esophagitis, inflammatory bowel diseases, Jaundice, & hepatitis, Cirrhosis, Diarrhea and Constipation, Drug-induced liver disease

UNIT - IV

Bone And Joint Disorders: Rheumatoid arthritis, Osteoarthritis, Gout, Osteoporosis

UNIT - V

Dermatological Diseases: Psoriasis, Eczema and scabies, impetigo, drug induced skin disorders Ophthalmology: Conjunctivitis, Glaucoma

REFERENCE BOOKS:

• 1. Roger and Walker. Clinical Pharmacy and Therapeutics – Churchill Livingstone publication
• 2. Joseph T. Dipiro et al. Pharmacotherapy: A Pathophysiologic Approach-Appleton & Lange
• 3. Robins SL. Pathologic basis of disease -W.B. Saunders publication
• 4. Eric T. Herfindal. Clinical Pharmacy and Therapeutics- Williams and Wilkins Publication
• 5. Lloyd Young and Koda-Kimble MA Applied Therapeutics: The clinical Use of Drugs-LWW
• 6. Chisholm- Burns Wells Schwinghammer Malone and Joseph P Dipiro. Pharmacotherapy Principles and practice-– McGraw Hill Publication
• 7. Carol Mattson Porth. Principles of Pathophysiology- Lippincott Williams and Wilkins
• 8. Harrison's. Principles of Internal Medicine - McGraw Hill
• 9. Clinical Pharmacy and Pharmacotherapeutics by Ravi Shankar, Pharma med Press
• 10. Pharmacotherapeutics by laxmi, Pharmamed Press. M.Pharm I Year I Sem (PHARMACY PRACTICE)