JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objective

This course aims to enable the students to understand the different treatment

approaches in managing various disease conditions. Also, it imparts knowledge and skills in optimizing drug therapy of a patient by individualizing the treatment plan through evidence-based medicines.

Course Outcome

Upon completion of this course it is expected that students shall be able to: -

Describe and explain the rationale for drug therapy - Summarize the therapeutic approach for management of various disease conditions including reference to the latest available evidence - Discuss the clinical controversies in drug therapy and evidence based medicine - Prepare individualized therapeutic plans based on diagnosis - Identify the patient specific parameters relevant in initiating drug therapy, and monitoring therapy (including alternatives, time- course of clinical and laboratory indices of therapeutic response and adverse effect/s)

UNIT - I

Nervous System: Epilepsy, Parkinson's disease, Stroke, Headache, Alzheimer’s disease, Neuralgias and Pain pathways and Pain management.

UNIT - II

Psychiatric Disorders: Schizophrenia, Depression, Anxiety disorders, Sleep disorders, Drug induced psychiatric disorders Renal system: Acute renal failure, Chronic renal failure, Renal dialysis, Drug induced renal disease

UNIT - III

Infectious Diseases I: General guidelines for the rational use of antibiotics and surgical prophylaxis, Urinary tract infections, Respiratory tract infections, Gastroenteritis, Tuberculosis, Malaria, Bacterial endocarditis, Septicemia.

UNIT - IV

Infectious Diseases II: Meningitis, HIV and opportunistic infections, Rheumatic fever, Dengue fever, H1N1, Helmenthiasis, Fungal infections. Gynecological disorders: Dysmenorrhea, Hormone replacement therapy.

UNIT - V

Oncology: General principles of cancer chemotherapy, pharmacotherapy of breast cancer, lung cancer, head & neck cancer, hematological malignancies, Management of nausea and vomiting, Palliative care

REFERENCE BOOKS:

• 1. Roger and Walker. Clinical Pharmacy and Therapeutics – Churchill Livingstone publication.
• 2. Joseph T. Dipiro et al. Pharmacotherapy: A Pathophysiologic Approach-Appleton & Lange
• 3. Robins SL. Pathologic basis of disease -W. B. Saunders publication
• 4. Eric T. Herfindal. Clinical Pharmacy and Therapeutics- Williams and Wilkins Publication
• 5. Lloyd Young and Koda-Kimble MA Applied Therapeutics: The clinical Use of Drugs- Lippincott Williams and Wilkins
• 6. Chisholm - Burns Wells Schwinghammer Malone and Joseph P Dipiro. Pharmacotherapy Principles and practice-– McGraw Hill Publication
• 7. Carol Mattson Porth. Principles of Pathophysiology- Lippincott Williams and Wilkins
• 8. Harrison's. Principles of Internal Medicine - McGraw Hill
• 9. Relevant review articles from recent medical and pharmaceutical literature M. Pharm I Year II Sem (PHARMACY PRACTICE)