JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Course Objective

This course is designed to impart basic knowledge and skills that are required to

practice quality use of medicines (QUM) in different healthcare settings and also to promote quality use of medicines, in clinical practice, through evidence-based medicine approach.

Course Outcomes

Upon completion of this course it is expected that students shall be able to:

• Understand the principles of quality use of medicines
• Know the benefits and risks associated with use of medicines
• Understand regulatory aspects of quality use of medicines
• Identify and resolve medication related problems
• Promote quality use of medicines
• Practice evidence-based medicines

UNIT - I

Introduction to Quality use of medicines (QUM): Definition and Principles of QUM, Key partners and responsibilities of the partners, Building blocks in QMC, Evaluation process in QMC, Communication in QUM, Cost effective prescribing.

UNIT - II

Concepts in QUM Evidence based medicine: Definition, concept of evidence-based medicine, Approach and practice of evidence-based medicine in clinical settings Essential drugs: Definition, need, concept of essential drug, National essential drug policy and list Rational drug use: Definition, concept and need for rational drug use, Rational drug prescribing, Role of pharmacist in rational drug use.

UNIT - III

QUM in various settings: Hospital settings, Ambulatory care/Residential care, Role of health care professionals in promoting the QUM, Strategies to promote the QUM, Impact of QUM on E-health, integrative medicine and multidisciplinary care. QUM in special population: Pediatric prescribing, Geriatric prescribing, prescribing in pregnancy and lactation, Prescribing in immune compromised and organ failure patients.

UNIT - IV

Regulatory aspects of QUM in India: Regulation including scheduling, Regulation of complementary medicines, Regulation of OTC medicines, Professional responsibility of pharmacist, Role of industry in QUM in medicine development.

UNIT - V

Medication errors: Definition, categorization and causes of medication errors, Detection and prevention of medication errors, Role of pharmacist in monitoring and management of medication errors Pharmacovigilance: Definition, aims and need for pharmacovigilance, Types, predisposing factors and mechanism of adverse drug reactions (ADRs), Detection, reporting and monitoring of ADRs, Causality assessment of ADRs, Management of ADRs, Role of pharmacist in pharmacovigilance.

REFERENCE BOOKS:

• 1. A Textbook of Clinical Pharmacy Practice – Essential concepts and skills –Parthasarathi G, Karin Nyfort-Hansen and Milap Nahata
• 2. Practical Drug Safety from A to Z By Barton Cobert, Pierre Biron, Jones and Bartlett Publishers.
• 3. Andrews EB, Moore N. Mann’s Pharmacovigilance
• 4. Dipiro JT, Talbert RL, Yee GC. Pharmacotherapy: A Pathophysiologic Approach
• 5. Straus SE, Richardson WS, Glasziou P, Haynes RB. Evidence-Based Medicine: How to practice and teach it
• 6. Cohen MR. Medication Errors
• 7. Online: http://medicinesaustralia.com.au/files/2012/05/MA_QUM_External_Reduced.pdf http://curriculum.racgp.org.au/statements/quality-use-of-medicines/ http://www.rug.nl/research/portal/files/14051541/Chapter_2.pdf
• 8. Relevant review articles from recent medical and pharmaceutical literature. M.Pharm I Year II Sem (Pharmacology)