JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

Prerequisite:

• 1. Fundamentals of Biotechnology
• 2. Basic biological Systems

Course Objectives:

The course is intended to cover fundamental terms and basics of biotechnology and building blocks; biological nanostructures, biosensors and biomedical applications of nanotechnology, nanodrugs and drug delivery systems.

Course Outcomes:

• To familiarize student with biological systems, materials, sensors and building blocks.
• To familiarize about biomedical applications, nanodrugs, molecular modeling of drugs and drugs delivery systems

UNIT - I

Fundamentals terms in biotechnology, Biological building blocks: Sizes of building blocks and Nanostructures, nucleic acids, genetic code and protein synthesis, DNA double nano wires, protein nanoparticles and polypeptide nanowires

UNIT - II

Biological Nanostructures: Bio-mimitics with examples, Bio mineralization, Bio compatible Bio sensors, Examples of proteins, micelles, vesicles, bilayers, and Multilayer films, application of bio- nanotechnology: bio nano machines, molecular modeling.

UNIT - III

Nano bio-sensors and biomedical applications, organic semiconductors, biological neurons and their functions, bio-chemical and quantum mechanical computers: DNA computers, parallel processing, Bit and ‘Q’ bit, Quantum parallelism.

UNIT - IV

Biomolecular sensing for cancer diagnostics using carbon nanotubes, nano devices in biomedical applications, nanoscale polymer fabrication for biomedical application, nanotechnology in cancer drug therapy: A biocomputational approach

UNIT - V

Introduction to drugs, Classification of drugs, Encapsulation of drugs, Nano drug delivery: Conventional drug delivery, targeted drug delivery, chemistry of drug delivery, role of nanotechnology in drug delivery, bionanoimaging, magnetic nanoparticles for MR imaging, Magnetic hyperthermia in cancer treatment

REFERENCE BOOKS:

• 1. Bio Nano Technology by Good Sell, Wiley Liss
• 2. Nanotechnology by John F. Mongillo
• 3. Introduction to Nanotechnology by Charles. P. Poole Jr and Frank J. Owens, Wiley India Pvt Ltd.
• 4. Nano Technology, A gentle introduction to the next big idea by Mark Ranter and Daniel Ranter, Pearson education
• 5. Nanotechnology – science, innovation and opportunity by Lynn E Foster, Prentice Hall- Pearson education.
• 6. Biological and Biomedical nanotechnology by Abraham P. Lee and L. James Lee
• 7. Biomedical Applications of Nanotechnology by Vinod Labhasetwar and Diandra L. Leslie - Pelecky
• 8. Biomedical Nanostructures by Kenneth E. Gonsalves, Craig R. Halberstadt, Cato T. Laurencin, Lakshmi S. Nair
• 9. Sensors, Nanoscience, Biomedical, Engineering and Instruments by Richord C.Dorf
• 10. Encyclopedia of Nanotechnology by H.S. Nalwa
• 11. Encyclopedia of Nanotechnology by M. Balakrishna Rao and K.Krishna Reddy (Vol I to X), Campus books.