JNTU
JNTU B.Pharmacy I Year PHARMACEUTICS- I Previous Question Paper (January-2020 - R17)
Note: This question paper contains two parts A and B. Part A is compulsory which carries 25 marks. Answer all questions in Part A. Part B consists of 5 Units. Answer any one full question from each unit. Each question carries 10 marks and may have a, b, c as sub questions.
PART- A
Define Posology. Write the equations used to calculate paediatric dose based on age.
Answer
Posology is the branch of pharmacy that deals with the study of doses or the quantitative study of drugs. The formulas based on age are Young's formula: Child dose = (Age in years / (Age in years + 12)) × Adult dose; and Dilling's formula: Child dose = (Age in years / 20) × Adult dose.
Classify the dosage forms with examples.
Answer
Dosage forms are classified into:
1. Solid dosage forms: Tablets, capsules, powders.
2. Liquid dosage forms: Syrups, elixirs, suspensions, emulsions.
3. Semisolid dosage forms: Ointments, creams, pastes, gels.
4. Gaseous dosage forms: Aerosols, inhalations.
Prepare 500ml of 70% alcohol from 90% alcohol.
Answer
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Write about advantages and disadvantages of liquid dosage forms.
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Define elixir and list out methods of preparation of elixirs.
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Explain about stability problems of emulsions.
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Write about types of suppositories.
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Rx Phenobarbitone sodium 600mg, Ammonium bromide 8 gm, Water upto 100ml. Make a mixture. Explain the incompatability in above preparation and how will you correct it.
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List out evaluation tests of semisolid dosage forms.
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Write about Pastes.
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PART- B
Write about Indian Pharmacopoeia.
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Explain about the factors affecting posology.
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Explain about errors in prescription.
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Write about preparation of effervescent powders with a suitable Formula.
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Find the concentration of sodium chloride (Freezing point -0.576°C) required to make 3% solution of Cocaine Hcl (Freezing point -0.090°C) iso-osmotic with blood plasma.
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Write about preparation of simple, compound and hygroscopic powders with examples.
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Define syrup and explain the methods of preparation of syrups with an example.
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Define Lotion and Liniment and write about them with examples.
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Supply 10 suppositories of theobroma oil each weighing 12 gm and Containing 3 gm of Iodoform. (Displacement Value of Iodoform Is 4.0).
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Write about evaluation of suppositories.
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Write in detail about physical and therapeutic incompatabilties with examples.
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Write about different ointment bases used in ointment and selection Criteria of ointment base selection.
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Write about preparation of Creams and gels.
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