JNTU
JNTU B.Pharmacy I Year HUMAN ANATOMY AND PHYSIOLOGY - II Previous Question Paper (June - 2022 - R17)
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Discuss various types of lung volumes and capacities with the help of spirograph and Draw neat labelled diagram of spirometer.
Answer
Lung volumes and capacities are measurements of the amount of air moved during breathing, which are recorded using a spirometer. The graphical representation of these volumes over time is called a spirogram.
Lung Volumes:
- Tidal Volume (TV): The volume of air inspired or expired during a normal, quiet breath, approximately 500 mL.
- Inspiratory Reserve Volume (IRV): The extra volume of air that can be forcibly inspired after a normal tidal inspiration, approximately 3000 mL.
- Expiratory Reserve Volume (ERV): The extra volume of air that can be forcibly expired after a normal tidal expiration, approximately 1100 mL.
- Residual Volume (RV): The volume of air remaining in the lungs after a maximal forced expiration, approximately 1200 mL; this cannot be measured by simple spirometry.
Lung Capacities:
- Inspiratory Capacity (IC): TV + IRV (approx. 3500 mL).
- Functional Residual Capacity (FRC): ERV + RV (approx. 2300 mL).
- Vital Capacity (VC): IRV + TV + ERV (approx. 4600 mL); the maximum amount of air exhaled after maximal inhalation.
- Total Lung Capacity (TLC): VC + RV (approx. 5800 mL).
Spirometer Diagram Description: A basic wet spirometer consists of an inverted bell suspended in a water-filled tank. A mouthpiece is connected via a tube to the air space inside the bell. As the subject breathes into the mouthpiece, the bell rises and falls. A pen attached to a counterweight records these movements on a rotating drum (kymograph), creating the spirogram tracing. The apparatus includes a soda lime container to absorb exhaled carbon dioxide and a valve system to allow fresh oxygen intake.
Discuss the process of digestion in detail along with anatomical diagram and functions of stomach.
Answer
Digestion is the process of breaking down complex food substances into simpler, absorbable forms through mechanical and chemical means. It begins in the mouth with mastication and salivary amylase action, continues in the stomach, and concludes primarily in the small intestine.
The stomach is a J-shaped muscular organ located in the upper left quadrant of the abdomen. Anatomically, it is divided into the cardia, fundus, body, and pylorus. Its primary functions include:
- Storage of food: The stomach acts as a reservoir, allowing for the gradual release of chyme into the small intestine.
- Mechanical digestion: Rhythmic contractions of the muscularis layer (churning) mix food with gastric juices to form chyme.
- Chemical digestion: Gastric glands secrete hydrochloric acid (HCl) and pepsinogen. HCl denatures proteins and activates pepsin, which initiates protein hydrolysis.
- Protection: Mucus secretion protects the stomach lining from self-digestion by acid and enzymes.
- Absorption: Limited absorption of substances like water, alcohol, and certain drugs occurs here.
The process involves the cephalic, gastric, and intestinal phases, regulated by both neural (vagus nerve) and hormonal (gastrin) mechanisms to ensure efficient nutrient breakdown.
Explain the role of Pepsin, Trypsin, Lipase, and Maltase in digestion process.
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Discuss the anatomy and functions of kidney with a neat labelled diagram.
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Discuss the regulation of blood pressure by RAS.
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Describe the various phases of the menstrual cycle.
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Discuss the role of estrogen and progesterone hormones in menstrual cycle.
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Describe how DNA serves as genetic information.
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Define genetics, genome, chromosome, genetic code and genotype.
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Explain the function of the lymphatic system: i) Red bone marrow ii) Thymus.
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Discuss the various mechanisms of Blood coagulation and mention the clotting disorders.
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With a neat diagram, explain the Anatomy of the Heart. Discuss the cardiac cycle.
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Mention the different heart sounds and their significances.
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Describe the physiology of urine formation.
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Discuss the composition and functions of blood.
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