JNTU
JNTU B.Pharmacy III INDUSTRIAL PHARMACY-I Previous Question Paper (December-2019 - R17)
Note: This question paper contains two parts A and B. Part A is compulsory which carries 25 marks. Answer all questions in Part A. Part B consists of 5 Units. Answer any one full question from each unit. Each question carries 10 marks and may have a, b as sub questions.
Part A
Relate crystalline and amorphous forms.
Answer
Crystalline forms possess a highly ordered, repeating internal molecular structure, whereas amorphous forms lack long-range order and exist in a disordered, glass-like state. Crystalline forms are generally more thermodynamically stable, while amorphous forms often exhibit higher solubility and dissolution rates due to their higher internal energy.
Define partition coefficient and give an equation.
Answer
The partition coefficient (P) is the ratio of the equilibrium concentrations of a substance dissolved in a two-phase system consisting of two largely immiscible solvents, typically octanol and water. It is expressed as:
where C(oil) and C(water) are the concentrations of the drug in the oil and aqueous phases, respectively.
Why film coating is better than sugar coating?
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What is coating?
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Compare hard and soft gelatin capsules.
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What is in process quality control of capsules?
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Summarize the advantages of parenterals.
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Compare large volume and small volume parenterals.
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What are cream bases? Give examples.
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Explain hair dye.
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Part B
Identify preformulation parameters for solid-dosage forms.
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Analyze the chemical properties of drugs for selection of dosage forms.
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Choose equipments for tablet compression.
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Evaluate suspensions and emulsions.
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Compose hard gelatin capsule manufacturing by different equipments (Manual, semiautomatic and automatic).
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Discuss about fluidized bed coater with neat diagram.
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Explain the good production procedures for parenterals. Write the evaluation of parenterals.
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Compare and contrast eye drops, eye ointments and eye lotions.
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Recommend the packaging materials suitable for liquid dosage forms.
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Discuss the principle, procedure and formulation of cold cream and vanishing cream.
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