JNTU
JNTU B.Pharmacy III PHARMACEUTICAL BIOTECHNOLOGY Previous Question Paper (February - 2023 - R17)
Question paper consists of Part A, Part B. Part A is compulsory, which carries 25 marks. In Part A, Answer all questions. In Part B, Answer any one question from each unit. Each question carries 10 marks and may have a, b as sub questions.
Part A
Definition of Enzyme Biotechnology.
Answer
Enzyme biotechnology is the application of enzymes, either in isolated form or within whole cells, as biological catalysts to perform specific chemical transformations for industrial, pharmaceutical, or analytical purposes.
What are Biosensors?
Answer
Biosensors are analytical devices that integrate a biological sensing element—such as an enzyme, antibody, or microorganism—with a physical transducer. The transducer converts the biological response into a measurable electrical, optical, or thermal signal proportional to the concentration of the target analyte.
What are cloning vectors?
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What are interferons?
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What is the definition and functions of MHC?
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Write about Cold Storage of Vaccines.
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Define ELISA.
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What is transduction?
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Explain about the sterilization methods.
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Explain Fermentation Methods.
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Part B
Explain about the Protein engineering.
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Describe the use of Microbes in Industry.
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Discuss the Methods of enzyme immobilization and applications.
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Describe the production of Amylase, Lipase and Pencillinase Enzymes.
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Explain about the PCR.
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What is Immunity? Explain about the humoral immunity.
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What are Restriction endonucleases? Explain them with example?
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Describe the Application of genetic engineering in medicine.
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Explain about the Structure of Immunoglobulins.
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Describe the Production, Purification and Applications of Hybridoma technology.
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Write about the Hypersensitivity reactions.
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Discuss the methods of the preparation of bacterial vaccines.
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What are the blotting techniques? Explain about Western blotting.
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Describe the Genetic organization of Eukaryotes.
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Explain about the Microbial genetics of transformation, plasmids and Transposons.
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Describe the Microbial Biotransformation and its Applications.
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Describe the Production of Penicillins and citric acid.
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Explain about the large scale production of fermenter design and its controls.
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Write about various types of media, equipments and Sterilization Methods.
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Explain about different types of mutation.
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