Jawaharlal Nehru Technological University Hyderabad
Jawaharlal Nehru Technological University Hyderabad B.Pharmacy I PHARMACEUTICS- I Previous Question Paper (December- 2018/ January-2019 - R17)
Note: This question paper contains two parts A and B. Part A is compulsory which carries 25 marks. Answer all questions in Part A. Part B consists of 5 Units. Answer any one full question from each unit. Each question carries 10 marks and may have a, b, c as sub questions.
PART- A
Define profession of pharmacy.
Answer
Pharmacy is the health profession that links health sciences with chemical sciences, charged with ensuring the safe, effective, and rational use of medications.
Classify dosage forms.
Answer
Dosage forms are classified based on their physical state into:
- Solid dosage forms (e.g., tablets, capsules, powders).
- Liquid dosage forms (e.g., solutions, suspensions, emulsions).
- Semi-solid dosage forms (e.g., ointments, creams, gels, suppositories).
- Gaseous dosage forms (e.g., aerosols, inhalers).
Convert empirical units to metric units. i) One Fl. ounce = .......... ml ii) One drachm = ...........mg
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Convert 35 O/P into %v/v alcohol.
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Mention the advantages of suspensions.
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Give one example of Throat Paint with formula.
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What are the disadvantages of suppositories?
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Identify the types of incompatibility in dispensing of following prescriptions. i) Rx : Strychnine HCl solution - 6 ml, Aromatic spirit of ammonia - 4 ml, Water - 120 ml ii) Rx : Sulfadiazine - 0.25 g, Sulphamerazine - 0.25 g, Ammonium chloride - 0.5 g Make a capsule
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Enlist the types of chemical permeation enhancers with suitable examples.
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Write a short note on gelling agents.
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PART-B
Give a note on IP and USP.
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Define a prescription. What are the elements of prescription? Give its importance.
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Explain the methods to calculate doses in paediatrics based on age and surface area.
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Explain any two methods for enhancing aqueous solubility of drugs with examples.
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Supply 10 suppositories of boric acid each weighing 5g, containing 3mg of boric acid. Displacement value of boric acid = 1.6.
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Discuss the special considerations required for dispensing the following types of powders. (i) Eutectic mixture, (ii) hygroscopic powders
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How do you prepare 600 ml of 60 % alcohol from 95% alcohol?
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Differentiate between lotion and liniments.
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Enumerate the stability problems of suspension and methods to overcome those instabilities.
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Classify emulsifying agents with suitable examples. Discuss their role in the formulation of stable emulsion.
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Discuss any three method of identification of types of emulsion.
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Define suppositories. Discuss various types of suppository bases.
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Mention any one method of preparation of suppository.
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Explain on therapeutic incompatability with examples. Suggest steps to overcome such incompatability.
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A mixture containing indiffusible substances is dispensed. What is the incompatibility? How it is overcome?
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Discuss about various vehicles used in the preparation of semisolid dosage form.
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Explain the method of preparation of creams with an example.
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Explain briefly how pastes, gels ointments and creams differ from each other.
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Write a note on mechanisms of dermal penetration of drugs.
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