JNTU
JNTU B.Pharmacy I BIOCHEMISTRY Previous Question Paper (December-2018 / January-2019 - R17)
This question paper contains two parts A and B. Part A is compulsory which carries 25 marks. Answer all questions in Part A. Part B consists of 5 Units. Answer any one full question from each unit. Each question carries 10 marks and may have a, b, c as sub questions.
PART- A
Define Diabetes Mellitus.
Answer
Diabetes Mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both, leading to disturbances in carbohydrate, fat, and protein metabolism.
Write a note on glycogen storage disease.
Answer
Glycogen storage diseases are a group of inherited metabolic disorders caused by enzyme deficiencies involved in the synthesis or degradation of glycogen. This leads to the accumulation of abnormal amounts or types of glycogen in tissues, primarily the liver and muscles, causing symptoms like hypoglycemia and hepatomegaly.
Write a note on phenylketonuria.
Answer
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Briefly explain: Transamination; deamination and decarboxylation reactions of amino acid metabolism.
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Define transcription and translation.
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Write a note on genetic code.
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Classify amino acids.
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Classify carbohydrates with suitable examples.
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Write are isoenzymes.
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Explain the allosteric regulation of enzymes.
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PART-B
Explain the gluconeogenesis pathway and mention its significance.
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Explain glycogen metabolism pathways.
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Explain the process of oxidative phosphorylation.
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Explain HMP shunt pathway and mention its significance.
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Explain the synthesis and biological significance of noradrenaline.
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Explain formation and utilization of ketone bodies.
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Write a note on steroidal hormones.
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Explain the oxidation pathway of palmitic acid.
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Explain the process of transcription and its regulation.
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Briefly describe the biosynthesis of purine nucleotides.
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Explain the disorders associated with purine catabolism.
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Explain the structure and functions of RNA.
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Explain the biological significance of ATP.
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Write a note on lipids.
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Explain the concept of free energy, enthalpy, entropy and redox potential.
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Explain the biological significance of cAMP.
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Explain the therapeutic and diagnostic applications of enzymes
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Discuss the classification of enzymes.
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Write a note on enzyme kinetics.
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Write a note on enzyme inhibitors with suitable examples.
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