JNTU
JNTU B.Pharmacy I Year PATHOPHYSIOLOGY Previous Question Paper (June-2019 - R17)
Note: This question paper contains two parts A and B. Part A is compulsory which carries 25 marks. Answer all questions in Part A. Part B consists of 5 Units. Answer any one full question from each unit. Each question carries 10 marks and may have a, b, c as sub questions.
Part A
Define hyperplasia and metaplasia.
Answer
Hyperplasia is an increase in the number of cells in an organ or tissue, leading to increased organ size. Metaplasia is a reversible change in which one adult cell type is replaced by another adult cell type better suited to withstand an adverse environment.
Mention the various mediators of inflammation.
Answer
Mediators of inflammation include vasoactive amines (histamine, serotonin), plasma proteases (kinin system, complement system, coagulation factors), arachidonic acid metabolites (prostaglandins, leukotrienes), cytokines (TNF-α, IL-1), and reactive oxygen species.
Define Hypertension.
Answer
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Write the difference between acute and chronic renal failure.
Answer
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Define diabetes and mention its types.
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Write a note on thyroid disorders.
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Define jaundice and mention its symptoms.
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Write a note on gout.
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Mention the causative organisms of tuberculosis and leprosy.
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Write a note on syphilis.
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Part B
Explain the wound healing process in detail.
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Write a note on homeostasis.
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Explain the etiopathogenesis of hypertension.
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Explain the cause and pathophysiology of acute renal failure.
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Explain the pathogenesis of Parkinson’s disease.
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Classify anemia based on red blood cell morphology and briefly explain each type.
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Explain the pathogenesis of rheumatoid arthritis.
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Write a note on: a) Carcinogens; b) Metastasis c) Systemic effects of cancer.
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Describe the mechanisms by which HIV virus infects a human cell.
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Write a note on meningitis and typhoid.
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