JNTU
JNTU B.Pharmacy II PHYSICAL PHARMACEUTICS-I Previous Question Paper (April - 2023 - R17)
Note: i) Question paper consists of Part A, Part B. ii) Part A is compulsory, which carries 25 marks. In Part A, answer all questions. iii) In Part B, Answer any one question from each unit. Each question carries 10 marks and may have a, b as sub questions.
Part A
Define dielectric constant and dipole moment.
Answer
Dielectric constant is a measure of a substance's ability to store electrical energy in an electric field, defined as the ratio of the permittivity of the substance to the permittivity of free space. Dipole moment is the product of the magnitude of the separated charges and the distance between them, indicating the polarity of a molecule.
What are eutectic mixtures? Mention its pharmaceutical significance.
Answer
Eutectic mixtures are solid mixtures of two or more substances that melt at a temperature lower than the melting points of the individual components. In pharmacy, they are significant for preparing topical powders and liquid preparations, though they require careful formulation to prevent unintended liquefaction during storage.
State and explain Raoult’s law.
Answer
Sign in to view the complete answer paper.
Write about ideal solubility parameters.
Answer
Sign in to view the complete answer paper.
Define compressibility index.
Answer
Sign in to view the complete answer paper.
Explain porosity and bulkiness of powders.
Answer
Sign in to view the complete answer paper.
What are complexes? Give one example.
Answer
Sign in to view the complete answer paper.
Define inclusion complex and chelating agent. Give one example for each.
Answer
Sign in to view the complete answer paper.
What are colligative properties?
Answer
Sign in to view the complete answer paper.
Write the applications of buffers in pharmacy.
Answer
Sign in to view the complete answer paper.
Part B
Explain the determination of sublimation critical point. Add a note on its application.
Answer
Sign in to view the complete answer paper.
Discuss the properties and significance of liquid crystal.
Answer
Sign in to view the complete answer paper.
Explain in detail the principle and working of polarimeter. Write a note on its application.
Answer
Sign in to view the complete answer paper.
Discuss the determination of dissociation constant.
Answer
Sign in to view the complete answer paper.
Explain the mechanisms of solute-solvent interactions. Add a note on solubility expressions.
Answer
Sign in to view the complete answer paper.
State distribution law. Write its limitations and applications.
Answer
Sign in to view the complete answer paper.
Discuss in details the diffusion principles in biological systems.
Answer
Sign in to view the complete answer paper.
Write a short note on azeotropic mixtures.
Answer
Sign in to view the complete answer paper.
Discuss the principle and working of air permeability method used to measure specific surface of particles.
Answer
Sign in to view the complete answer paper.
Enumerate the application of micromeritics in pharmacy.
Answer
Sign in to view the complete answer paper.
Explain the determination of particle size by microscopy and sedimentation method.
Answer
Sign in to view the complete answer paper.
Write a short note on the determination of permeability and adsorption of particles.
Answer
Sign in to view the complete answer paper.
Give classification of complexation. Discuss about crystalline structures of complexes and organic molecular complexes.
Answer
Sign in to view the complete answer paper.
Write a short on thermodynamic treatment of stability constants.
Answer
Sign in to view the complete answer paper.
Enumerate different methods of analysis of complex. Explain any two methods of analysis of complexes.
Answer
Sign in to view the complete answer paper.
Define buffer capacity. Deduce buffer equation for weak base and its salt.
Answer
Sign in to view the complete answer paper.
Write a note on pharmaceutical buffers.
Answer
Sign in to view the complete answer paper.
What is isotonicity? Explain the adjusting tonicity by sodium chloride equivalent and cryoscopic method
Answer
Sign in to view the complete answer paper.
Explain buffered isotonic solutions.
Answer
Sign in to view the complete answer paper.