JNTU
JNTU B.Pharmacy I Year BIOCHEMISTRY Previous Question Paper (September/October - 2023 - R17)
Note: i) Question paper consists of Part A, Part B. ii) Part A is compulsory, which carries 25 marks. In Part A, answer all questions. iii) In Part B, Answer any one question from each unit. Each question carries 10 marks and may have a, b as sub questions.
Part A
What is diabetes mellitus?
Answer
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia resulting from defects in insulin secretion, insulin action, or both, leading to disturbances in carbohydrate, fat, and protein metabolism.
What are glycogen storage diseases?
Answer
Glycogen storage diseases are a group of inherited metabolic disorders caused by genetic enzyme deficiencies that affect glycogen synthesis, glycogen breakdown, or glucose utilization, resulting in the abnormal accumulation of glycogen in tissues like the liver and muscles.
Explain hypercholesterolemia.
Answer
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What is atherosclerosis?
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What is hyperuricemia?
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What is gout disease?
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Explain biological role of nucleic acids and proteins.
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Write enthalpy and entropy.
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What is Michaelis plot?
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What is line Weaver Burke plot?
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Part B
Describe the pathway, energetics, and significance Citric acid cycle.
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Explain glucose-6-Phosphate dehydrogenase (G6PD) deficiency.
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Explain the steps involved in gluconeogenesis.
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Explain electron transport chain (ETC) and its mechanism.
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Describe the catabolism of phenylalanine and their metabolic disorders.
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Explain the De novo synthesis of fatty acids.
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What are essential fatty acids? Explain the disorders of lipid metabolism.
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Give synthesis and significance of 5-HT and melatonin.
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Discuss the catabolism of purine nucleotides.
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Give the structure of DNA and their functions.
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Write the structure of RNA and their functions.
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Explain the biosynthesis of purine.
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Define and classify carbohydrates with examples. Explain their biological functions.
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Explain biological significance of ATP and cyclic AMP.
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Define and classify amino acids with examples. Give their biological functions.
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What is redox potential? Explain its importance in bioenergetics.
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Explain the principle and applications of radio immune assay.
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Explain the types of reversible enzyme inhibitors with examples.
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Define enzymes. Write the IUB classification of enzymes with examples.
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Give the structure and biochemical functions of coenzymes.
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