JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD B. Pharmacy I PATHOPHYSIOLOGY Previous Question Paper (April - 2023 - R17)
Note: i) Question paper consists of Part A, Part B. ii) Part A is compulsory, which carries 25 marks. In Part A, answer all questions. iii) In Part B, Answer any one question from each unit. Each question carries 10 marks and may have a, b as sub questions.
Part A
Enumerate the various types of cellular adaptation with examples
Answer
Cellular adaptations include: Atrophy (e.g., muscle wasting due to disuse), Hypertrophy (e.g., cardiac muscle enlargement due to hypertension), Hyperplasia (e.g., endometrial thickening), Metaplasia (e.g., squamous metaplasia in smokers' airways), and Dysplasia (e.g., cervical intraepithelial neoplasia).
List out the Chemical mediators and their role in the process of inflammation.
Answer
Key mediators include: Histamine (vasodilation and increased vascular permeability), Prostaglandins (pain and fever), Leukotrienes (bronchospasm and chemotaxis), and Cytokines (e.g., IL-1, TNF-α, which mediate systemic inflammatory responses and fever).
Define Atherosclerosis? Summarize the risk factors of atherosclerosis.
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Enumerate the Pathological changes in COPD.
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Summarize the etiopathogensis of hemophilia.
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Discuss the various androgenic factors of male and female to cause infertility.
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Elaborate the etiological and risk factor for Cancer
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Discuss the Etiology, clinical symptoms and diagnosis of Jaundice.
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Name the causative agent, mode of transmission, signs, and symptoms for Urinary tract infections.
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Discuss the etiology, symptoms and clinical diagnosis of Meningitis.
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Part B
Explain etiology, Pathogenesis and morphology of reversible cell injury.
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Enumerate the pathogenesis of cellular events of Inflammation.
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Discuss the factors affecting wound healing.
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Explain the process of apoptosis.
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Write a note on myocardial infraction and its clinical diagnosis.
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Discuss the etiopathogensis of acute and chronic renal failure.
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Discuss the pathogenesis chronic bronchitis.
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Explain the etipathogensis and its clinical diagnosis of Congestive heart failure.
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Enumerate different types of seizures. Discuss the pathogenesis of Epilepsy.
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Enlist the various types of stroke. Discuss the pathogenesis of ischemic stroke.
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Write about thyroid diseases.
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Discuss the etiology, clinical manifestations and diagnosis of Schizophrenia.
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Discuss the risk factors and pathogenesis of rheumatoid arthritis.
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Discuss the pathogenesis of inflammatory bowel diseases.
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Discuss the etiopathogensis of cancer.
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Explain the Etiopathogensis of alcoholic liver disease.
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Explain the pathogenesis of urinary tract infection.
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Discuss the life cycle of the AIDS virus.
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Discuss the clinical symptoms and explain the pathogenesis of Leprosy.
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Explain the Etiopathologensis and Clinical Diagnosis of Tuberculosis.
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