JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD B.Pharmacy II PHARMACOLOGY-I Previous Question Paper (May - 2019 - R17)
Note: This question paper contains two parts A and B. Part A is compulsory which carries 25 marks. Answer all questions in Part A. Part B consists of 5 Units. Answer any one full question from each unit. Each question carries 10 marks and may have a, b, c as sub questions.
Part A
Write Idiosyncracy effects.
Answer
Idiosyncrasy is an abnormal or unexpected drug reaction that is genetically determined and occurs in a small percentage of the population. It is not dose-dependent and does not involve the typical pharmacological mechanism of the drug.
What are Essential drugs?
Answer
Essential drugs are those that satisfy the priority health care needs of the majority of the population. They are selected based on disease prevalence, evidence of efficacy and safety, and comparative cost-effectiveness, and should be available at all times in adequate amounts and appropriate dosage forms.
How Ion channel receptors help in signaling?
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Write dose response relationship.
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Write uses of d-tubocurarine.
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Write uses of prazocin.
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Name any two inhibitory neurotransmitter.
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Write mechanism of action of baclofen.
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Name any two anti-maniac drugs.
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What is Tolerance?
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Part B
Define pharmacokinetics. Enumerate the factors affecting pharmacokinetics.
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Why Enzyme induction is important? What are the problem encounter and prevent it.
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Write different routes of drug elimination.
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What are Pharmacokinetic drug interaction? Explain briefly with examples.
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Write different types of Clinical trials.
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With a neat diagram explain various types of drug receptors.
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Classify sympathomimetics. Write the MOA, adverse effect and uses of adrenaline.
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Write side effects of Organophosphorus compound poisoning and how do you treat them.
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Write the uses of Neostigmine.
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Elaborate the neurotransmission in brain with emphasis on various neurotransmitters.
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Write the classification of anti-epileptics? Explain phenytoin MOA.
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Name different general anesthetics and write stages of anesthesia.
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Write Levodopa uses and MOA.
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What are Tricyclic antidepressants and classify them.
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Classify antipsychotics. Write the MOA, adverse effect and uses of chlorpromazine.
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