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JNTU B.Pharmacy II PHARMACEUTICAL ORGANIC CHEMISTRY-III Previous Question Paper (November/December -2020 - R17)

B.Pharmacy | II | II | R17 | November/December -2020

Answer PaperPaper Code: 244AAMaximum Marks: 75Time: 2 hours

Answer any five questions

All questions carry equal marks

Main

1
Explain the following terms with examples.
15 marks
a
Optical isomerism
3 marks

Answer

Optical isomerism is a form of stereoisomerism where molecules have the same molecular formula and connectivity but differ in their spatial arrangement, resulting in the ability to rotate the plane of plane-polarized light. This occurs in molecules containing a chiral center, such as lactic acid, which exists as two non-superimposable mirror-image forms.

b
Optical activity
3 marks

Answer

Optical activity is the property of a substance to rotate the plane of plane-polarized light. Substances that rotate light to the right are termed dextrorotatory (+), while those that rotate it to the left are levorotatory (-). An example is the rotation of light by a solution of (+)-glucose.

c
Enantiomerism
3 marks

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d
Diasterioisomerism
3 marks

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e
Polarimeter
3 marks

Answer

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215 marks
a
What is Racemic modification? Explain
7 marks

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b
Write brief about the reactions of chiral molecules with examples.
8 marks

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315 marks
a
Mention a note on the methods of determination of configuration of geometrical isomers.
7 marks

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b
Explain the chair and boat conformational isomers of cyclohexane and Discuss about the stability.
8 marks

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415 marks
a
Describe the stereoisomerism in biphenyl compounds.
8 marks

Answer

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b
Write a note on E, Z isomerism with examples.
7 marks

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5
What are hetero cyclic compounds? Classify them with examples. Write the synthetic reactions and medicinal uses of pyrrole.
15 marks

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6
Explain the synthesis, reaction, medicinal uses, relative aromaticity and reactions of thiophene.
15 marks

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7
Give the synthesis, reactions and medicinal uses of oxazole and thiazole.
15 marks

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8
Explain the clemmensen reduction and wolff kishner reduction with few examples.
15 marks

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About this paper

This page contains the question paper of PHARMACEUTICAL ORGANIC CHEMISTRY-III from JNTU for B.Pharmacy II II, November/December -2020, R17.

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