Jawaharlal Nehru Technological University Hyderabad
Jawaharlal Nehru Technological University Hyderabad B.Pharmacy II PHARMACEUTICAL MICROBIOLOGY Previous Question Paper (May/June-2019 - R17)
Part A is compulsory which carries 25 marks. Answer all questions in Part A. Part B consists of 5 Units. Answer any one full question from each unit. Each question carries 10 marks.
Part A
Define pharmaceutical microbiology.
Answer
Pharmaceutical microbiology is a specialized branch of microbiology that deals with the study of microorganisms associated with the manufacture of pharmaceutical products, including the prevention of microbial contamination and the development of antimicrobial agents.
Give the scope and importance of microbiology.
Answer
The scope includes the study of microbial spoilage, sterility testing, and the development of vaccines and antibiotics. Its importance lies in ensuring the safety, quality, and efficacy of pharmaceutical products by preventing contamination and monitoring the manufacturing environment.
What is sterilization and classify with examples.
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Write the principle involved in physical method of sterilization.
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What are fungi give examples.
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Define and classify disinfectants with examples.
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Mention the different sources of contamination in an aseptic area.
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Give the clean area classification with suitable examples.
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Mention the sources and types of microbial contaminants.
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Write the applications of cell cultures.
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Part B
Explain the history and various branches of microbiology. Write a note on isolation and preservation methods for pure cultures.
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Write the morphological classification of bacteria with a neat labelled diagram. Explain the quantitative measurement of bacterial growth with suitable examples.
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Explain the various steps involved in the staining techniques. Write principle and procedure involved in sterilization.
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Explain the general steps involved in the identification of bacteria. Give the applications of chemical method of sterilization.
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Explain the mode of action of disinfectants. Write a note on the sterility testing of ophthalmic products as per IP.
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Write the morphology and cultivation of virus with a neat labelled diagram. Explain the sterility testing of liquid products as per IP.
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Explain the designing of aseptic area with a flow chart. Write the method for standardization of vitamins.
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Explain the working process of laminar flow equipment with a neat labelled diagram. Write the principle involved and a method for microbiological assay.
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Mention the various factors affecting the microbial spoilage of pharmaceutical products. Explain the general procedure for cell cultures with examples.
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Write the various steps involved in the assessment of microbial contamination and spoilage. Enumerate the applications of cell cultures in pharmaceutical industry and research.
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